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Other significant adverse effects of testosterone supplementation include acceleration of pre-existing prostate cancer growth in individuals who have undergone androgen deprivation; increased hematocrit , which can require venipuncture in order to treat; and, exacerbation of sleep apnea .  Adverse effects may also include minor side-effects such as acne and oily skin, as well as, significant hair loss and/or thinning of the hair, which may be prevented with 5-alpha reductase inhibitors ordinarily used for the treatment of benign prostatic hyperplasia , such as finasteride .  Exogenous testosterone may also cause suppression of spermatogenesis , leading to, in some cases, infertility.  It is recommended that physicians screen for prostate cancer with a digital rectal exam and prostate-specific antigen (PSA) level before starting therapy, and monitor PSA and hematocrit levels closely during therapy. 
Due to the fact that methenolone does not aromatize, estrogenic side effects are of no concern with this compound. This is another reason why it is often utilized by bodybuilders during their pre-contest preparations. Water retention, gynecomastia, and a rise in blood pressure should not occur from use of methenolone. Due to this, there is no need for anti-estrogen or anti-aromatase compounds while cycling this drug. In fact, there is some evidence that methenolone can act as an anti-estrogen itself, much in the same way that drostanolone does. However this effect is weak and should not be relied up for these purposes.
Testosterone enanthate ( USAN , BAN ) (brand names Delatestryl , Testostroval , Testro LA , Andro LA , Durathate , Everone , Testrin , Andropository ), or testosterone heptanoate , is an androgen and anabolic steroid and a testosterone ester .    Along with testosterone cypionate and testosterone propionate , it is one of the most widely used testosterone esters.  Testosterone enanthate was first introduced in 1952.  Administered via intramuscular injection , it is the most widely used form of testosterone in androgen replacement therapy . 
The second theory is similar and is known as "evolutionary neuroandrogenic (ENA) theory of male aggression".   Testosterone and other androgens have evolved to masculinize a brain in order to be competitive even to the point of risking harm to the person and others. By doing so, individuals with masculinized brains as a result of pre-natal and adult life testosterone and androgens enhance their resource acquiring abilities in order to survive, attract and copulate with mates as much as possible.  The masculinization of the brain is not just mediated by testosterone levels at the adult stage, but also testosterone exposure in the womb as a fetus. Higher pre-natal testosterone indicated by a low digit ratio as well as adult testosterone levels increased risk of fouls or aggression among male players in a soccer game.  Studies have also found higher pre-natal testosterone or lower digit ratio to be correlated with higher aggression in males.     
Primobolan side effects include that of cardiovascular strain and negative cholesterol changes, which is a side effect shared among all anabolic steroids. This involves the reduction of HDL (the good cholesterol) and increases of LDL (the bad cholesterol). The result of such changes is an increased risk of arteriosclerosis, and the degree to which these changes occur for the worse are usually dose-dependent (with higher doses increasing the negative changes and the risks). Other factors that affect these negative cholesterol changes are: duration of use, and route of administration. In terms of the route of administration, oral anabolic steroids are known as being the worst for their negative impacts on cholesterol in comparison to injectable anabolic steroids. This is where oral anabolic steroids hold a negative reputation for exhibiting a far worse negative impact on cholesterol in comparison to injectable anabolic steroids. This is due to the fact that the liver is essentially the body’s cholesterol processing and production center, and increased hepatotoxicity as a result of oral anabolic steroid use is associated with negative cholesterol changes.
Testosterone enanthate ( USAN , BAN ) (brand names Delatestryl , Testostroval , Testro LA , Andro LA , Durathate , Everone , Testrin , Andropository ), or testosterone heptanoate , is an androgen and anabolic steroid and a testosterone ester .    Along with testosterone cypionate and testosterone propionate , it is one of the most widely used testosterone esters.  Testosterone enanthate was first introduced in 1952.  Administered via intramuscular injection , it is the most widely used form of testosterone in androgen replacement therapy .